Magnetic resonance imaging perfusion to assess transmural flow distribution
نویسنده
چکیده
Cardiovascular magnetic resonance (CMR) is increasingly used to assess non-invasively the presence and the extent of myocardial ischemia. CMR perfusion has been shown to be superior to nuclear perfusion imaging, allows high-resolution quantitative assessment of myocardial perfusion reserve, has been validated against invasive reference standards and microspheres and therefore has the potential to become the noninvasive and radiation-free test of choice to guide patients’ clinical decision making. The higher spatial resolution of CMR is thought to be one the key factors explaining the superior diagnostic capabilities of CMR visual assessment when compared with other ischemia imaging techniques.
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Magnetic resonance imaging of myocardial perfusion in single-vessel coronary artery disease: implications for transmural assessment of myocardial perfusion.
The purpose of the study was to investigate the potential of magnetic resonance imaging (MRI) to assess transmural differences in myocardial perfusion. Contrast-enhanced MRI was performed at rest and during hyperemia in a dog model and in 22 patients with single-vessel coronary artery disease. From MR signal intensity-versus-time curves, three perfusion parameters were derived: maximum myocardi...
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